Inkjet Microarray Applications
Small Molecule Microarrays
Cost-effective compound screening
HIGH-THROUGHPUT DRUG DISCOVERY
Fast, cost-effective hit detection
Small molecule microarrays are a fast, reliable, cost-effective method of compound library screening. Immobilise whole compound libraries onto functionalised slides for convenient screening against your target.
Ideal for groups who are
- screening for binding interactions against a protein of interest
- targeting RNA structures to modulate disease at the translation level
- developing PROTACs for targeted protein degradation, or DUBTACs for targeted protein stabilisation
- training and testing AI-powered drug discovery systems
Integrate an Arrayjet instrument into your in-house discovery pipelines for high-throughput microarray printing with minimal manual input and sample use. Or, outsource to our experienced application scientists for assay development, primary screening, and microarray manufacture.
Arrayjet’s CRO / CMO services include access to a deeply-annotated catalogue of 11.5 billion compounds from Chemspace, which features curated panels for different molecule types and target groups.
Increase your throughput
The Inkjet Advantage
Our systems allow for reliable walk-away operation and deliver highly reproducible microarrays at unrivalled speed.
Print in DMSO
Printing at 10 mM directly in DMSO means there are no extra liquid handling steps.
Conserve your sample
We require just 0.5 µl of sample to produce 1000 screening slides.
Never miss a hit
Quality is assured with AI-driven software for 100% deposition yield.
Meet commercial targets
Our inkjet microarrayers have the capacity and speed to meet your throughput demands.
Choose your surface chemistry
Our range of assay surfaces includes specially developed isocyanate slides as well as epoxy.
Choose a compound library
Screening and manufacturing services include access to ready-designed panels from Chemspace.
Instruments and services are delivered from our ISO 13485:2016 controlled manufacturing facility.
RECOMMENDED INSTRUMENT PACKAGE
Mercury Microarray Spotter for Small Molecule Screening
The first commercial platform for small molecule microarrays. Combines the world-class printing of a Mercury instrument with a scanner, optimised consumables, and proprietary protocols for high-throughput compound screening.
The Mercury 100-S outputs 100 slides per batch. Load up to 18,400 samples (48 x 384-well plates) at once, reload as required.
Ultra-low-volume high density dispensing of spots 40 pL / 50 µm in size. Print a whole library on one microarray slide.
Highly parallel loading from 384-well plates. Aspirate 0.5 µl sample to print 1000 slides.
Real-time quality assurance with automatic spot-reprint for 100% yield, full data traceability and proof of sample printing.
Printing takes place in a HEPA-filtered environment with temperature and humidity controlled and monitored for consistency.
Auto-loading fluorescence scanner for rapid and reliable data acquisition and sensitive hit detection.
Intuitive management of layouts and data
Customise print layouts, track samples, manage data, view operational records. 12 months Pro licence included with package.
Proprietary isocyanate or epoxy slides, optimised printing and cleaning buffers, plates, JetGuard™ sample protectors, and incubation chambers.
CUSTOM MICROARRAY SERVICES
Outsource to our
Arrayjet Advance™ Team
Access our microarray application expertise and the fastest, most versatile microarray printers, when you outsource your development and manufacturing projects to us.
COMBINATORIAL LIBRARY SCREENING
ArrayPlex™ Spot-On-Spot Microarrays
Arrayjet’s unique inkjet approach to bioprinting allowed us to develop ArrayPlex™ – our patented microarray platform. With ArrayPlex™ we can create multi-layered microarrays, allowing two libraries to be screened against each other. This takes throughput to the next level, generating millions of data points each week.
ArrayPlex™ is compatible with all sample types and detects hits at an equal or higher sensitivity to ELISA.
Let's work together
TELL US ABOUT YOUR PROJECT
Our scientists will work to understand your needs and deliver a microarray solution for you. If you have an idea for a project – we’re excited to hear it.
