Arrayjet

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FOX v.2.4.0
3 2-d Aldehyde polyan

PolyAn 2-D Aldehyde (25 pack)

£228

SKU AJC2011 Category

Product Code  104 00 301

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Product Description

Arrayjet offers a broad PolyAn product portfolio including plastic and glass slides as well as functionalized 96-well plates for DNA, peptide or protein applications ranging from low-density microarrays and diagnostic tests to ultra-dense arrays for high-throughput screening.

PolyAn 2D-aldehyde slides are manufactured from high-quality glass with an ultra-flat surface and low background fluorescence.  The glass is coated with a thin aldehyde layer that will covalently bind most biomolecules.

The slides are easy to work with and are fully compatible with all Arrayjet microarray printers and all slide scanners.

Technical Info

Aldehyde groups bind to Amines, Hydrazines and Aminoalkoxyacetyl modified biomolecules. In an intermediate state the Aldehydes form an instable Imine-group with Amines (Schiff-base).

In order to increase the bond strength it is possible to reduce the Imines with NaCNBH3 to form stable Amines.

Upon completion of the coupling reaction non-reacted aldehydes must be blocked with small molecules that penetrate the 3D-Matrix and effectively quench all remaining reactive groups.

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